Fields of Interest: Parkinson's disease and Schizophrenia

English Version

El doctor Gabriel de Erausquin recibió su título de Médico de la Universidad de Buenos Aires en 1986, y a comienzos del año siguiente entró como becario al Consejo Nacional de Investigaciones Científicas y Técnicas de la Argentina. Sus investigaciones sobre los efectos farmacológicos de la hormona vasopresina sobre la conducta animal y humana le merecieron el grado de Doctor en Medicina, otorgado por la Universidad de Buenos Aires en 1990. Su tesis recibió la calificación de Sobresaliente. Luego de dos años de perfeccionamiento postdoctoral en la Universidad Georgetown, el doctor de Erausquin completó la residencia de psiquiatría y un año de especialización en neuroimágenes en la Universidad Yale, y la residencia de neurología en la Universidad Washington. El doctor de Erausquin es especialista en neurología y en psiquiatría reconocido por el American Board of Psychiatry and Neurology de los Estados Unidos de América, y actualmente se desempeña como profesor asistente de ambas especialidades en la Universidad Washington, en Saint Louis. Sus trabajos de investigación han recibido amplio reconocimiento internacional, incluyendo el Young Investigator Award de la Sociedad Internacional de Esquizofrenia, el APA-Dista Residents Research Award de la American Psychiatric Association, el S Weir Mitchell Award de la American Academy of Neurology, el Joint Junior Faculty Award de la United Parkinson Foundation y la Parkinson Disease Foundation, y el Klerman Award en Psiquiatría Clínica de NARSAD. El Dr.de Erausquin ha sido nombrado investigador Stephen and Constance Lieber, e investigador Sydney R. Baer Jr.

Aleman GG, de Erausquin GA, Micheli F
Cognitive disturbances in primary blepharospasm.
Mov Disord. 2009 Oct 30;24(14):2112-20.
Abstract

Anastasia A, Torre L, de Erausquin GA, Masco DH
Enriched environment protects the nigrostriatal dopaminergic system and induces astroglial reaction in the 6-OHDA rat model of Parkinson’s disease.
J Neurochem. 2009 May;109(3):755-65. Epub 2009 Feb 20.
Abstract

Zorumski CF, de Erausquin G, Dokucu M, Svrakic D, Garcia K, Jarvis M
Brain stimulation & the treatment of refractory psychiatric disorders.
Mo Med. 2008 Jan-Feb;105(1):57-61.
Abstract

Tabbal SD, Revilla FJ, Mink JW, Schneider-Gibson P, Wernle AR, de Erausquin GA, Perlmutter JS, Rich KM, Dowling JL
Safety and efficacy of subthalamic nucleus deep brain stimulation performed with limited intraoperative mapping for treatment of Parkinson’s disease.
Neurosurgery. 2007 Sep;61(3 Suppl):119-27; discussion 127-9.
Abstract

Anastasia A, de Erausquin GA, Wojnacki J, Masco DH
Protection of dopaminergic neurons by electroconvulsive shock in an animal model of Parkinson’s disease.
J Neurochem. 2007 Nov;103(4):1542-52. Epub 2007 Sep 13.
Abstract

Mamah D, Wang L, Barch D, de Erausquin GA, Gado M, Csernansky JG
Structural analysis of the basal ganglia in schizophrenia.
Schizophr Res. 2007 Jan;89(1-3):59-71. Epub 2006 Oct 30.
Abstract

Dorsey DA, Masco DH, Dikranian K, Hyrc K, Masciotra L, Faddis B, Soriano M, Gru AA, Goldberg MP, de Erausquin GA
Ultrastructural characterization of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid-induced cell death in embryonic dopaminergic neurons.
Apoptosis. 2006 Apr;11(4):535-44.
Abstract

Calvo de Padilla M, Padilla E, Gonzalez Aleman G, Bourdieu M, Guerrero G, Strejilevich S, Escobar JI, Svrakic N, Cloninger CR, de Erausquin GA
Temperament traits associated with risk of schizophrenia in an indigenous population of Argentina.
Schizophr Res. 2006 Apr;83(2-3):299-302. Epub 2006 Feb 9.


Strejilevich SA, Palatnik A, Avila R, Bustin J, Cassone J, Figueroa S, Gimenez M, de Erausquin GA
Lack of extrapyramidal side effects predicts quality of life in outpatients treated with clozapine or with typical antipsychotics.
Psychiatry Res. 2005 Feb 28;133(2-3):277-80.
Abstract

de Erausquin GA
Transactivation of cell death signals by glutamate transmission in dopaminergic neurons.
Crit Rev Neurobiol. 2004;16(1-2):107-19.
Abstract

Zhang PL, Santos JM, Newcomer J, Pelfrey BA, Johnson MC, de Erausquin GA
Impact of atypical antipsychotics on quality of life, self-report of symptom severity, and demand of services in chronically psychotic patients.
Schizophr Res. 2004 Nov 1;71(1):137-44.
Abstract

Moulder KL, Meeks JP, Shute AA, Hamilton CK, de Erausquin G, Mennerick S
Plastic elimination of functional glutamate release sites by depolarization.
Neuron. 2004 May 13;42(3):423-35.
Abstract

Bremner JD, Bronen RA, De Erasquin G, Vermetten E, Staib LH, Ng CK, Soufer R, Charney DS, Innis RB
Development and Reliability of a Method for Using Magnetic Resonance Imaging for the Definition of Regions of Interest for Positron Emission Tomography.
Clin Positron Imaging. 1998 Jun;1(3):145-159.
Abstract

de Erausquin GA, Hyrc K, Dorsey DA, Mamah D, Dokucu M, Masco DH, Walton T, Dikranian K, Soriano M, Garcia Verdugo JM, Goldberg MP, Dugan LL
Nuclear translocation of nuclear transcription factor-kappa B by alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors leads to transcription of p53 and cell death in dopaminergic neurons.
Mol Pharmacol. 2003 Apr;63(4):784-90.
Abstract

Abi-Dargham A, Laruelle M, Krystal J, D’Souza C, Zoghbi S, Baldwin RM, Seibyl J, Mawlawi O, de Erasquin G, Charney D, Innis RB
No evidence of altered in vivo benzodiazepine receptor binding in schizophrenia.
Neuropsychopharmacology. 1999 Jun;20(6):650-61.
Abstract

Abi-Dargham A, Gandelman MS, DeErausquin GA, Zea-Ponce Y, Zoghbi SS, Baldwin RM, Laruelle M, Charney DS, Hoffer PB, Neumeyer JL, Innis RB
SPECT imaging of dopamine transporters in human brain with iodine-123-fluoroalkyl analogs of beta-CIT.
J Nucl Med. 1996 Jul;37(7):1129-33.
Abstract

Isaacs KR, de Erausquin G, Strauss KI, Jacobowitz DM, Hanbauer I
Differential effects of excitatory amino acids on mesencephalic neurons expressing either calretinin or tyrosine hydroxylase in primary cultures.
Brain Res Mol Brain Res. 1996 Feb;36(1):114-26.
Abstract

de Erausquin G, Brooker G, Costa E, Hanbauer I
Persistent AMPA receptor stimulation alters i homeostasis in cultures of embryonic dopaminergic neurons.
Brain Res Mol Brain Res. 1994 Feb;21(3-4):303-11.
Abstract

de Erausquin G, Brooker G, Hanbauer I
K(+)-evoked dopamine release depends on a cytosolic Ca2+ pool regulated by N-type Ca2+ channels.
Neurosci Lett. 1992 Oct 12;145(2):121-5.
Abstract

de Erausquin GA, Manev H, Guidotti A, Costa E, Brooker G
Gangliosides normalize distorted single-cell intracellular free Ca2+ dynamics after toxic doses of glutamate in cerebellar granule cells.
Proc Natl Acad Sci U S A. 1990 Oct;87(20):8017-21.
Abstract